Our list of featured projects is a testament to our continued growth! Our projects range from Phase II - Phase IV clinical trials to patient registries and qualitative research.
A Randomized, Double-Blinded Controlled Trial Comparing High vs. Standard Dose Oseltamivir in Severe, Influenza Infection in ICU. Anand Kumar, M.D. – Manitoba Health Sciences Centre. ROSII is a randomized, double-blinded controlled trial. The primary objective is to compare the antiviral efficacy of a 10 day course of standard and high-dose oseltamivir in the treatment of severe influenza infections. An important secondary objective of the trial is to determine the difference in the numbers of ventilator days between the standard-dose and high-dose groups. View more CTU projects...
The Ontario Citizens' Council: A qualitative film-based evaluation using Brokered Dialogue. Dr. Janet Parsons and Dr. Jim Lavery - Applied Health Research Centre, St. Michael's Hospital. The Ontario Citizen’s Council (OCC) was established to provide public input on strategic priorities and specific funding issues to the Ontario Public Drug Programs. We were engaged to evaluate this new public engagement initiative over its first two years, using a new film-based research method we have developed called Brokered Dialogue. View more OEQRU projects...
A Virtual Ward to Reduce Readmissions after Hospital Discharge. Dr. Irfan Dhalla - St. Michael's Hospital. The main objective of the Virtual Ward study is to perform a pragmatic, randomized controlled trial to compare admission to a Virtual Ward following hospital discharge with usual care. Whether admission to a Virtual Ward reduces readmission, death, emergency department visits and/or long-term care admission will be evaluated. View more CTU Projects...
Dr. Jonathon Maguire - St. Michael's Hospital, University of Toronto, Dr. Patricia Parkin and Dr. Catherine Birken – The Hospital for Sick Children, University of Toronto. TARGetKids! (Toronto Applied Research Group) is a prospective registry enrolling healthy children aged 0-5 years. The aim of the registry is to link early nutritional exposures to later health outcomes including obesity, micronutrient deficiency, and developmental outcomes. More OEQRU projects...
Membranous Nephropathy Trial Of Rituximab. Dr. Fernando C. Fervenza – Mayo Clinic & Dr. Daniel Cattran, University Health Network. MENTOR is a multi-center randomized controlled Phase III trial that tests whether B cell targeting with Rituximab is more effective, reduces the number of relapses, and leads to an improved quality of life when compared with treatment with Cyclosporine in patients with IMN. View more CTU projects...
Province of Ontario Neurodevelopmental Disorders (POND) Network. Evdokia Anagnoustou, M.D. - Bloorview Research Institute. AHRC is developing a large clinical database of children and youth with Neurodevelopmental Disorders, which will allow to properly characterize these children using behavioural / cognitive measures, imaging and electrophysiology techniques, genomics and epigenomics in order to advance scientific understanding of these disorders. View more OEQRU projects...
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